Dynavax Technologies

Research Associate II/III

Job Location US-CA-Berkeley
Posted Date 2 weeks ago(2/13/2018 5:27 PM)
ID
18-021N
Category
R&D

Overview

This position will be responsible for supporting research activities that advance Dynavax’s immuno-oncology research programs in the field of Toll Receptor agonism

Responsibilities

  • Will conduct research activities with small molecule, oligonucleotide and/or protein-based drug candidates, including; compound formulation, sample management, analytical method development / optimization, and bioconjugation. 
  • Contribute to the design and execution of in vitro and in vivo PK/DM experiments. 
  • Execute experimental protocols and collect / record results. 
  • Analyze experimental data, prepare and submit technical reports, and present results at project team and departmental meetings. 
  • Coordinate day-to-day laboratory activities to ensure reagents are available and maintenance of equipment. 
  • Document all scientific work in lab notebooks, follow established Dynavax standard operating procedures on data documentation and notebooks, and adhere to Dynavax Quality Systems standards. 
  • Support the organization in maintaining a work environment focused on quality and that fosters learning, open communication, collaboration, integration, and team work. 
  • Other duties as assigned.

 

Qualifications

  • BS or MS in life science, either in chemistry, biochemistry and/or other related discipline. 
  • Required experience will vary depending on level: RA II level with BS and 3+ years relevant experience; RA III level with BS and 5+ years, or an MS with 2+ years’ of relevant experience. 
  • Relevant laboratory experience includes:
  • Small molecule / oligonucleotide / protein compound formulation and management.
  • Purification / analysis of small molecules, oligonucleotides, and / or proteins by high or low pressure LC methods (RP, SEC, HIC, etc.).
  • Other analytical methods, including SDS-PAGE, UV spectroscopy, DLS, zeta-potential, endotoxin determination, etc.
  • Familiarity with bioconjugation chemistries / methodology.
  • Experience with harvesting tissues from laboratory mice and processing for bioanalysis.

 Proficiency with Word, Excel, PowerPoint, Prism, and ChemDraw software. 

  • Must be capable of working independently, have careful attention to experimental details, and possess excellent record-keeping and strong organizational skills.  
  • Excellent written and verbal communication skills. 

Additional knowledge and skills desired, but not required:

Mass spectroscopy and its application to the field of biotechnology.

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